发明人：
GERSTENHABER, JONATHAN, A. | LELKES, PETER, I.
摘要：
The present invention includes a robotic system for the enhanced automation, manipulation, and control of electroprocessing in two or three dimensions. In one embodiment, the system includes a sealed chamber devoid of any electrical or conductive components which would interfere with the electrical field and eventual material fabrication, while still allowing for two-dimensional and three-dimensional robot motion. In certain embodiments, the system of the invention produces materials or scaffolds with complex shapes, including materials with ridges, valleys, curves, and the like, which are difficult or impossible to construct using traditional systems.
权利要求：
CLAIMS
What is claimed:
1. A robotic electroprocessing system, comprising:
a spinneret head;
at least three linear actuators connected to the spinneret head; a target; and
a motor that drives movement of the linear actuators;
wherein the target, the spinneret head and the at least three linear actuators are positioned in an environmentally sealed chamber.
2. The system of claim 1, wherein each of the at least three actuators are connected to a first end of one or more arms, wherein the second end of the one or more arms are connected to the spinneret head.
3. The system of claim 2, wherein the arms are connected to the actuators and head using universal joints providing at least two degrees of freedom.
4. The system of claim 1, wherein the head comprises one or more needles capable of being electrified.
5. The system of claim 4, wherein the one or more needles are connected via tubing to one or more fluidic pumps located exterior to the chamber.
6. The system of claim 1, wherein the chamber provides a controlled isolated environment.
7. The system of claim 1, wherein the chamber further comprises one or more auxiliary electrodes.
8. The system of claim 1, wherein each of the at least three actuators comprises a movable carriage connected to the spinneret head, wherein the carriage moves along the actuator as driven by the motor, thereby moving the spinneret head.
9. The system of claim 8, wherein the motor is a stepper motor which turns a screw of the actuator, thereby moving the carriage.
10. The system of claim 4, wherein the chamber is devoid of conductive materials which would interfere with an electrical field generated by voltage supplied to the needle.
11. The system of claim 1 , wherein the spinneret head moves in three dimensions in order to provide a constant distance along the Z-axis, between the head and the target, while moving along the X or Y axis, thereby allowing for electroprocessing onto targets with surfaces of irregular heights for the production of irregular shaped material.
12. The system of claim 1, wherein the head moves at a resolution of less than about ΙΟμιη.
13. The system of claim 1, wherein the target rotates.
14. The system of claim 13, wherein the rotation of the target allows for coating of irregular shaped 3-D materials.
15. The system of claim 1, wherein the system further comprises a computing device which controls the movement of the head and environment within the chamber.
16. A method of manufacturing a material comprising the steps of:
providing the robotic electroprocessing system of claim 1 ; administering a fluid comprising at least one component to be deposited to at least one needle positioned on the head; and producing an electrical field between the needle and the target, thereby depositing the component onto the target.
17. The method of claim 16, wherein the method comprises moving the head in three-dimensions to deposit the component at a desired location of the target.
18. The method of claim 16, comprising depositing the component onto a surface having irregular heights by moving the head to provide a constant distance along the Z-axis between the head and the target, while moving along the X or Y axis.
19. The method of claim 18, wherein the method produces irregular shaped materials.
20. The method of claim 16, wherein the material is biocompatible.
21. The method of claim 16, wherein the component is chosen from a group consisting of a natural component, synthetic component, and a biological component.
22. The method of claim 16, wherein the generated electrical field and the location of component deposition is not interfered with by the presence of conductive materials within the chamber.
23. The method of claim 16, wherein the material is a scaffold for tissue engineering.
24. The method of claim 16, wherein the method comprises electroprocessing of at least one component and printing of at least one component.
25. The method of claim 16, wherein the method comprises electrospinning of at least one component and electrospraying of at least one component.
26. The method of claim 16, further comprising rotating the target, thereby depositing the component onto a rotating target.
27. The method of claim 26, wherein the method coats irregular shaped 3-
D materials.