摘要：
A method for the treatment of spider silk filament for use as a thread or composition in the manufacture of cosmetic, medical, textile, and industrial applications, wherein the spider silk filament, derived from genetically modified organisms, is treated with at least one component selected from the group consisting of vitamins, hormones, antioxidants, chelating agents, antibiotics, preserving agents, fragrances, dyes, pigments, magnetic nanoparticles, nanocrystals, cell adhesion enhancers, thermal insulators, shrinkage agents and cosmetic, medical or dermatological active substances. Textile fabrics obtained by this method are stronger, bio-compatible, bio-degradable and have a higher thermal conductivity. Treated spider silk filament can also be applied in an oil-in-water or water-in-oil protective cream that is hypoallergenic and ensures a firmer skin.
权利要求：
C L A I M S
1. A Method for the treatment of spider silk filament for use as thread or a composition in the manufacture of cosmetic, medical, textile or industrial applications, comprising the steps of:
(A) providing spider silk filament derived from genetically modified organisms;
(B) treating of the spider silk filament with at least one component selected from the group consisting of vitamins, hormones, antioxidants, chelating agents, antibiotics, preserving agents, fragrances, dyes, pigments, magnetic nanoparticles, nanocrystals, cell adhesion enhancers, thermal insulators, shrinkage agents and cosmetic, medical or dermatological active substances.
2. The method of claim 1, wherein the spider silk filament is obtained by a wet- or
electrospinning process of spider silk protein derived from genetically modified organisms.
3. A method for the manufacture of a cosmetic, medical, textile or industrial-thread, based on spider silk filament according to claim 1, 2, manufactured by the twining, cabling or braiding of two or more spider silk filaments. 4. Spider silk thread according to claim 3, wherein the spider silk thread is textured.
5. A method for the manufacture of a cosmetic, medical or industrial textile fabric and / or support structure, based on spider silk thread according to claim 3, 4, comprising the steps of:
mechanically two-or three-dimensional weaving, braiding and / or knitting of the spider silk thread to form a stronger, more flexible, enlarged total surface area, which is suitable for use in heat exchange with a medium such as solids, liquids and gases, as well as for the application as a support structure for liquids which harden or organic materials which grow together, as well as for general use in strengthening surfaces.
6. Textile fabric and / or support structure obtained by the method according to claim 5, wherein the total surface area obtained is tuned in such a way that the increased thermal conductivity can be optimally utilized for its application.
7. Textile fabric and / or support structure according to claim 6, wherein the textile
fabric is dyed matt black or the used spider silk filament is black by manipulation of the GMO, so as to be able to optimally absorb solar heat.
8. Textile fabric and / or support structure according to claim 6, 7 wherein the obtained fabric is partly thermally insulated to reduce heat loss to a minimum.
9. Textile fabric and / or support structure according to claim 7, for use in a solar
collector for solar water heaters, solar air heating, compression refrigeration, absorption cooling and water extraction on the basis of these techniques.
10. Textile fabric and / or support structure obtained according to the method of claim 5, characterized in that the fabric has a significantly increased resistance against hard impacts.
11. Textile fabric and / or support structure obtained according to the method of claim 5, characterized in that the fabric has a considerably better adhesion with skin. 12. Textile fabric and / or support structure obtained according to the method of claim 5, characterized in that the construct is bio-degradable at a controlled rate.
13. Textile fabric and / or support structure obtained according to the method of claim 5, characterized in that the construct is biocompatible.
14. Textile fabric and / or support structure obtained according to the method of claim 5, characterized in that the construct stimulates cell growth.
15. A method for the manufacture of a bio-artificial tissue or skin tissue, comprising the steps of:
(A) providing textile fabric and /or support structure according to claim 11-14;
(B) treating of the textile fabric and / or support structure with at least one component selected from the group consisting of fibroblasts, keratinocytes and other cells and tissues.
16. Artificial tissue or skin tissue obtained according to the method of claim 15,
characterized in that the artificial tissue has a remarkable "growth" and stimulates stem cell production.
17. Artificial tissue or skin tissue obtained according to the method of claim 15,
characterized in that the artificial tissue is a bulletproof construct, that has significantly enhanced resistance against hard impacts.
18. A method for the manufacture of a hardenable textile- or industrial construct comprising the steps of:
(A) providing textile fabric and / or support structure obtained according to the method of claim 5;
(B) treating of the textile fabric and / or support structure with at least one component selected from the group consisting of hardeners like rubber, plastics, synthetic materials, cement, concrete, kombucha and other organic and synthetic hardeners. 19. A method for the manufacture of a composition with dissolved spider silk protein, based on spider silk filament obtained according to the method of claim 1, 2.
20. A method for the manufacture of a non-woven construct, in the form of a foam or gel, based on a composition with dissolved spider silk protein, obtained according to the method of claim 19, produced by salt leaching, gas foaming, phase separation, or other known techniques, characterized in that the construct has the same
characteristics as claims 5-18.
21. A method for the manufacture of a medical, cosmetic oil-in-water or water-in-oil skin-protective cream, comprising the steps of:
(A) providing a composition with the dissolved spider silk protein, according to claim 19;
(B) treating of the composition with at least one component selected from the group consisting of surfactants, fillers, oils, fats, water, emulsifiers and other ingredients for cosmetic, medical or dermatological creams.