Bio-ink formulations, bio-printed corneal lenticule, and applications thereof

公开(公告)号：
GB202202470D0
公开(公告)日：
2022-04-06
申请号：
GB2022002470
申请日：
2020-07-27
授权日：
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受理局：
英国
专利类型：
发明申请
简单法律状态：
失效
法律状态/事件：
撤回-未指定类型
IPC分类号：
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战略新兴产业分类：
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国民经济行业分类号：
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当前申请(专利权)人：
PANDORUM TECHNOLOGIES PRIVATE LIMITED
原始申请(专利权)人：
PANDORUM TECHNOLOGIES PRIVATE LIMITED
当前申请(专利权)人地址：
Incorporated in India, GKVK Post, Bellary Road, Bengaluru 560 065, India
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摘要：
The present disclosure discloses a xeno-free bio-ink formulation amenable to be printed using a 3D printer. The bio-ink formulation exhibits optimum viscosity in the range of 1690-5300 cP. The present disclosure discloses a bio-printed corneal lenticule obtained from the bio-ink formulation. The bio-printed corneal lenticule as disclosed is of the optimum thickness in the range of 10-500 microns and exhibits transmittance in the range of 80-99%. The present disclosure also discloses a process for preparing the bio-ink formulation as well as for preparing the bio-printed corneal lenticule. Further, the present disclosure discloses a method of treating a corneal defect using the bio-printed corneal lenticule as an implant to treat the corneal defect. The bio-printed corneal lenticule can further be used as a model for in-vitro drug testing and diseases modelling.
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