摘要：
A method of manufacturing pre-formed, customized, ceramic, labial/lingual orthodontic clear aligner attachments (CCAA) by additive manufacturing (AM) may comprise measuring dentition data of a profile of teeth of a patient, based on the dentition data, creating a three dimensional computer-assisted design (3D CAD) model of the patient's teeth using reverse engineering, and saving the 3D CAD model, designing a 3D CAD structure model for one or more CCAA on various parts of each tooth, importing data related to the 3D CAD CCAA structure model into an AM machine, directly producing the CCAA in the ceramic slurry-based AM machine by layer manufacturing, enabling the provider to deliver patient-specific CCAA's by an indirect bonding method to the patient's teeth to improve the efficacy and retention of the clear aligners.
权利要求：
CA 03102465 2020-12-02 WO 2019/241251 PCT/US2019/036556 CLAIMS What is claimed is: 1. A method of manufacturing pre-formed, customized, ceramic, labial/lingual orthodontic clear aligner attachments (CCAA) by additive manufacturing (AM), said method comprising: measuring dentition data of a profile of teeth of a patient; based on the dentition data, creating a three dimensional computer-assisted design (3D CAD) model of the patient's teeth using reverse engineering, and saving the 3D CAD model; designing a 3D CAD structure model for one or more CCAA on various parts of each tooth; importing data related to the 3D CAD CCAA structure model into an AIVI machine; directly producing the CCAA in the ceramic slurry-based AIVI machine by layer manufacturing to form a patient-specific CCAA by an indirect bonding method, the patient-specific CCAA adapted to the patient's teeth.
2. The method of claim 1, wherein the additive manufacturing machine uses a slurry- based process.
3. The method of claim 2, wherein the slurry-based process includes at least one of lithography-based manufacturing, inkjet printing, slip casting, laser lithography additive manufacturing, direct light processing, and selective laser melting.
4. The method of claim 1, wherein the CCAA is made of an inorganic material with at least one component selected from a group of materials including an oxide ceramic, a nitride CA 03102465 2020-12-02 WO 2019/241251 PCT/US2019/036556 ceramic, a carbide ceramic, Aluminum Oxide (A1203), Zirconium Oxide (Zr02), Alumina- toughened Zirconia (ATZ), Zirconia-toughened alumina (ZTA), Lithium disilicate, Leucite silicate and Silicon Nitride.
5. The method of claim 1, wherein the 3D CAD CCAA structure model includes data defining a fracture wall around a perimeter of a base of the CCAA.
6. The method of claim 5, wherein the fracture wall has a thickness of about 10 ¨ about
15. m, inclusive.
7. The method of claim 6, wherein the fracture wall is adapted provide predictable fracture of the wall upon application of the normal force, enabling debonding of the CCAA through a combination of tensile and peeling forces.
8. The method of claim 7, wherein the normal force is applied in at least one of a mesial- distal direction, an occlusal-gingival direction, or to any opposite corners.
9. The method of claim 8, wherein the combination of tensile and peeling forces is less than a shear bond strength of a bonded CCAA.
10. The method of claim 1, wherein the 3D CAD CCAA structure model includes data representing at least a) the CCAA base (bonding area) that has recesses and/or undercuts into the bonding surface of the CCAA that are custom-shaped to fit the negative of a labial/lingual tooth CA 03102465 2020-12-02 WO 2019/241251 PCT/US2019/036556 surface, and contact a particular area of a tooth surface, c) a CCAA material, d) the particular tooth's profile, and e) a CCAA guide or indirect bonding jig to guide 3-dimensional placement of the CCAA onto the tooth.
11. The method of claim 1, wherein the ceramic slurry-based AM machine comprises: a molding compartment comprising a platform and a plunger to directly produce the CCAA by layer manufacturing; a material compartment; and an LED light source for digital light processing, wherein the CCAA is produced by layer manufacturing using slicing software to separate the 3D CAD CCAA structure model into layers and to get a horizontal section model for each layer so that a shape of each layer produced by the ceramic slurry-based AIVI machine is consistent with the 3D CAD structure data.
12. The method of claim 1, wherein the ceramic slurry-based AIVI machine comprises: a vat adapted to hold the CCAA during manufacturing; a horizontal build platform adapted to be held at a settable height above the vat bottom; an exposure unit, adapted to be controlled for position selective exposure of a surface on the horizontal build platform with an intensity pattern with predetermined geometry; a control unit, adapted to receive the 3D CAD CCAA structure model and, using the 3D CAD CCAA structure model to: polymerize in successive exposure steps layers lying one above the other on the build platform, respectively with predetermined geometry, by controlling the exposure unit, and CA 03102465 2020-12-02 WO 2019/241251 PCT/US2019/036556 to adjust, after each exposure step for a layer, a relative position of the build platform to the vat bottom, to build up the object successively in the desired form, which results from the sequence of the layer geometries.
13. The method of claim 12, wherein the exposure unit further comprises a laser as a light source, a light beam of which successively scans the exposure area by way of a movable mirror controlled by the control unit.
14. The method of claim 1, wherein directly producing the CCAA by layer manufacturing further comprises: in an apparatus comprising: a vat with an at least partially transparently or translucently formed horizontal bottom, into which light polymerizable material can be filled, a horizontal build platform adapted to be held at a settable height above the vat bottom, an exposure unit adapted to be controlled for position selective exposure of a surface on the build platform with an intensity pattern with predetermined geometry, comprising a light source refined by micromirrors to more precisely control curing, a control unit adapted for polymerizing in successive exposure steps layers lying one above the other on the build platform; controlling the exposure unit so as to selectively expose a photo-reactive slurry in the vat; adjusting, after each exposure for a layer, a relative position of the build platform to the vat bottom; and CA 03102465 2020-12-02 WO 2019/241251 PCT/US2019/036556 building up the CCAA successively in the desired form, resulting from the sequence of the layer geometries. 15. The method of claim 14, wherein the exposure unit further comprises a laser as a light source, a light beam of which successively scans the exposure area by way of a movable mirror controlled by the control unit.
16. The method of claim 15, wherein a scanning accuracy (trueness, per tooth) is less than
0.025 mm and the precision is less than 0.100mm.
17. The method of claim 14, wherein a manufacturing accuracy in the z-axis of the ceramic slurry-based AIVI machine is from 5 to about 60 p.m, and wherein the accuracy is achieved by using a between layer additive error compensation method based on a calculated amount of polymerization shrinkage, to prevent errors in the CCAA base morphology.
18. The method of claim 14, wherein manufactured layers of the CCAA comprise a material selected from the group consisting of high strength oxide ceramics including Aluminum Oxide (A1203) and Zirconium Oxide (Zr02) and may be mono- or polycrystalline filled ceramic.
19. The method according to claim 14, wherein the CCAA is less than 3.00 mm thick from the nearest tooth bonding surface to its outer edges.
20. The method of claim 1, wherein the 3D CAD model is saved as a 3D vector file format. CA 03102465 2020-12-02 WO 2019/241251 PCT/US2019/036556
21. The method of claim 1, wherein the thickness of the manufactured layers is from 5 to 100 micrometers (um) based on the resolution requirements of the CCAA for proper retention to the clear aligner.